孕早期阴道出血与早产风险的关系。

Risk of preterm delivery in relation to vaginal bleeding in early pregnancy.

作者信息

Hossain Rydhwana, Harris Tenecia, Lohsoonthorn Vitool, Williams Michelle A

机构信息

Department of Epidemiology, Multidisciplinary International Research Training Program, University of Washington, School of Public Health and Community Medicine, Seattle, WA 98195, USA.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2007 Dec;135(2):158-63. doi: 10.1016/j.ejogrb.2006.12.003. Epub 2007 Jan 4.

DOI:10.1016/j.ejogrb.2006.12.003

PMID:17207901

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2726845/

Abstract

OBJECTIVE

To examine the relationship between vaginal bleeding during early pregnancy and preterm delivery.

METHODS

Study subjects (N=2678) provided information regarding socio-demographic, biomedical, and lifestyle characteristics. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (95% CI).

RESULTS

Any vaginal bleeding in early pregnancy was associated with a 1.57-fold increased risk of preterm delivery (95% CI: 1.16-2.11). Vaginal bleeding was most strongly related with spontaneous preterm labor (OR=2.10) and weakly associated with preterm premature rupture of membrane (OR=1.36) and medically induced preterm delivery (OR=1.32). As compared to women with no bleeding, those who bled during the first and second trimesters had a 6.24-fold increased risk of spontaneous preterm labor; and 2-3-fold increased risk of medically induced preterm delivery and preterm premature rupture of membrane, respectively.

CONCLUSION

Vaginal bleeding, particularly bleeding that persists across the first two trimesters, is associated with an increased risk of preterm delivery.

摘要

目的

探讨孕早期阴道出血与早产之间的关系。

方法

研究对象（N = 2678）提供了有关社会人口统计学、生物医学和生活方式特征的信息。采用逻辑回归来估计比值比（OR）和95%置信区间（95%CI）。

结果

孕早期出现任何阴道出血与早产风险增加1.57倍相关（95%CI：1.16 - 2.11）。阴道出血与自发性早产的相关性最强（OR = 2.10），与胎膜早破（OR = 1.36）和医源性早产（OR = 1.32）的相关性较弱。与无出血的女性相比，在孕早期和孕中期出血的女性发生自发性早产的风险增加6.24倍；发生医源性早产和胎膜早破的风险分别增加2 - 3倍。

结论

阴道出血，尤其是在前两个孕期持续存在的出血，与早产风险增加有关。

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孕早期阴道出血与早产风险的关系。

Risk of preterm delivery in relation to vaginal bleeding in early pregnancy.

作者信息

Hossain Rydhwana, Harris Tenecia, Lohsoonthorn Vitool, Williams Michelle A

机构信息

Department of Epidemiology, Multidisciplinary International Research Training Program, University of Washington, School of Public Health and Community Medicine, Seattle, WA 98195, USA.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2007 Dec;135(2):158-63. doi: 10.1016/j.ejogrb.2006.12.003. Epub 2007 Jan 4.

DOI:10.1016/j.ejogrb.2006.12.003

PMID:17207901

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2726845/

Abstract

OBJECTIVE

To examine the relationship between vaginal bleeding during early pregnancy and preterm delivery.

METHODS

RESULTS

CONCLUSION

Vaginal bleeding, particularly bleeding that persists across the first two trimesters, is associated with an increased risk of preterm delivery.

摘要

目的

探讨孕早期阴道出血与早产之间的关系。

方法

研究对象（N = 2678）提供了有关社会人口统计学、生物医学和生活方式特征的信息。采用逻辑回归来估计比值比（OR）和95%置信区间（95%CI）。

结果

结论

阴道出血，尤其是在前两个孕期持续存在的出血，与早产风险增加有关。

孕早期阴道出血与早产风险的关系。

Risk of preterm delivery in relation to vaginal bleeding in early pregnancy.

作者信息

机构信息

出版信息

OBJECTIVE

METHODS

RESULTS

CONCLUSION

目的

方法

结果

结论

相似文献

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孕早期阴道出血与早产风险的关系。

Risk of preterm delivery in relation to vaginal bleeding in early pregnancy.

作者信息

机构信息

出版信息

OBJECTIVE

METHODS

RESULTS

CONCLUSION

目的

方法

结果

结论