Bosch M Espinosa, Sánchez A Ruiz, Rojas F Sánchez, Ojeda C Bosch
Department of Analytical Chemistry, Faculty of Sciences, University of Málaga, Campus Teatinos, 29071 Málaga, Spain.
J Pharm Biomed Anal. 2007 Feb 19;43(3):799-815. doi: 10.1016/j.jpba.2006.12.005. Epub 2006 Dec 15.
The present article reviews the methods of determination published for morphine and its metabolites covering the period from 1980 until at the first part of 2006. The overview includes the most relevant analytical determinations classified in the following two types: (1) non-chromatographic methods and (2) chromatographic methods.