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复发性和残留性青少年血管纤维瘤

Recurrent and residual juvenile angiofibromas.

作者信息

Tyagi I, Syal R, Goyal A

机构信息

Neuro-otology Unit, Department of Neuro-surgery, Sarjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.

出版信息

J Laryngol Otol. 2007 May;121(5):460-7. doi: 10.1017/S0022215107005592. Epub 2007 Jan 9.

Abstract

INTRODUCTION

In the surgical management of juvenile nasopharyngeal angiofibromas the possibility of recurrences and residual tumours is always there. This study was undertaken to predict the prognostic factors determining recurrence of juvenile nasopharyngeal angiofibroma and to find out the usual sites of these tumours.

MATERIAL AND METHODS

The medical records of 95 patients with histologically proven juvenile nasopharyngeal angiofibroma were reviewed retrospectively. The commonest surgical approach used was a combined transpalatal and transmaxillary approach with a lazy S incision. A conservative lateral infratemporal approach was used in three cases.

RESULTS

Complete removal of the juvenile nasopharyngeal angiofibroma was achieved in 78 (82 per cent) of the cases in a single operation. A residual tumour was found in 17 (18 per cent) cases and recurrences occurred in 13 (13.7 per cent) cases.

CONCLUSIONS

Extensions into the pterygoid fossa and basisphenoid, erosion of the clivus, intracranial extensions medial to the cavernous sinus, invasion of the sphenoid diploe through a widened pterygoid canal, feeders from the internal carotid artery, a young age and a residual tumour were risk factors found associated with recurrence of juvenile nasopharyngeal angiofibroma.

摘要

引言

在青少年鼻咽血管纤维瘤的外科治疗中,复发和残留肿瘤的可能性始终存在。本研究旨在预测决定青少年鼻咽血管纤维瘤复发的预后因素,并找出这些肿瘤的常见部位。

材料与方法

回顾性分析95例经组织学证实的青少年鼻咽血管纤维瘤患者的病历。最常用的手术方法是经腭和经上颌联合入路,采用“L”形切口。3例采用保守的颞下外侧入路。

结果

78例(82%)患者在一次手术中实现了青少年鼻咽血管纤维瘤的完全切除。17例(18%)发现有残留肿瘤,13例(13.7%)出现复发。

结论

翼腭窝和蝶骨基底部受累、斜坡侵蚀、海绵窦内侧的颅内扩展、通过增宽的翼管侵犯蝶骨板障、颈内动脉供血、年龄较小以及残留肿瘤是发现的与青少年鼻咽血管纤维瘤复发相关的危险因素。

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