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成人发病的青少年型鼻血管纤维瘤。

'Juvenile' nasal angiofibroma presenting in adulthood.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Beaumont Hospital, Dublin, Ireland

Department of Otolaryngology-Head and Neck Surgery, Beaumont Hospital, Dublin, Ireland.

出版信息

BMJ Case Rep. 2023 Jun 19;16(6):e254391. doi: 10.1136/bcr-2022-254391.

Abstract

Juvenile nasopharyngeal angiofibromas (JNAs) are rare hyper vascular, benign tumours typically demonstrating a locally aggressive growth pattern. The cardinal presenting symptoms are unilateral nasal obstruction and recurrent, spontaneous epistaxis. Cases outside the adolescent male population are exceedingly rare and present a diagnostic challenge. We present the case of a man in his 30s referred to our tertiary skull base centre, presenting with left nasal obstruction. Examination showed left nasopharyngeal fullness without a discrete mass. Cross-sectional imaging detailed a 2.5×2.1×1.3 cm mass localised to his left sphenoid sinus with bony erosion. Due to the suspicion of malignancy, multidisciplinary consensus was to perform a diagnostic excisional biopsy and this revealed a JNA. He remains clinically well and asymptomatic following surgery. This case highlights the potential for subtle symptomatology in the presentation of these tumours and the challenge in diagnosing a JNA outside the adolescent male population.

摘要

青少年鼻咽血管纤维瘤(JNAs)是一种罕见的高血管良性肿瘤,通常表现出局部侵袭性生长模式。主要表现症状为单侧鼻塞和反复发作的自发性鼻出血。青春期男性以外的病例极为罕见,诊断具有挑战性。我们报告了一例 30 多岁的男性患者,因左侧鼻塞被转诊至我们的三级颅底中心。检查显示左侧鼻咽饱满,但无明显肿块。横断面成像详细显示了一个 2.5×2.1×1.3 厘米的肿块,位于他的左侧蝶窦,伴有骨侵蚀。由于怀疑恶性肿瘤,多学科共识是进行诊断性切除活检,结果显示为 JNA。手术后,他仍无症状,临床情况良好。该病例强调了这些肿瘤表现出的潜在微妙症状,以及在青春期男性以外的人群中诊断 JNA 的挑战性。

相似文献

1
'Juvenile' nasal angiofibroma presenting in adulthood.成人发病的青少年型鼻血管纤维瘤。
BMJ Case Rep. 2023 Jun 19;16(6):e254391. doi: 10.1136/bcr-2022-254391.
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Bilateral juvenile nasopharyngeal angiofibroma: report of a case.双侧青少年鼻咽血管纤维瘤:一例报告
Int Forum Allergy Rhinol. 2014 Jul;4(7):603-6. doi: 10.1002/alr.21322. Epub 2014 Mar 24.
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An unusual case of epistaxis-juvenile nasopharyngeal angiofibroma.鼻出血-青少年鼻咽血管纤维瘤的罕见病例。
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本文引用的文献

1
Nasopharyngeal Angiofibroma: A Forgotten Entity in Older Patients.鼻咽血管纤维瘤:老年患者中被遗忘的疾病
Clin Med Insights Case Rep. 2019 Apr 23;12:1179547619841062. doi: 10.1177/1179547619841062. eCollection 2019.
3
Juvenile nasopharyngeal angiofibroma.青少年鼻咽血管纤维瘤
J Oral Maxillofac Pathol. 2016 May-Aug;20(2):330. doi: 10.4103/0973-029X.185908.
10
Recurrent and residual juvenile angiofibromas.复发性和残留性青少年血管纤维瘤
J Laryngol Otol. 2007 May;121(5):460-7. doi: 10.1017/S0022215107005592. Epub 2007 Jan 9.

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