Duggan Michelle, Kavanagh Brian P
Department of Anesthesia, Mayo General Hospital, Castlebar, Co. Mayo, Ireland.
Curr Opin Anaesthesiol. 2007 Feb;20(1):37-42. doi: 10.1097/ACO.0b013e328011d7e5.
To report the impact of atelectasis on perioperative outcomes. Atelectasis occurs in the dependent parts of the lungs of most patients who are anesthetized. Development of atelectasis is associated with decreased lung compliance, impairment of oxygenation, increased pulmonary vascular resistance and development of lung injury. Here, we examine the etiology, contributing factors, consequences, diagnosis and treatment of atelectasis.
Atelectasis describes the state of absent air in alveoli attributable to collapse, but recent findings suggest that alveoli are filled with foam and fluid. It is now known that atelectasis plays an important role beyond abnormal gas exchange and that prevention or reversal of atelectasis in some populations of postoperative patients may improve outcome.
Atelectasis in the presence of preexisting lung disease or limited cardiopulmonary reserve may have significant consequences. Increasing understanding of the underlying nature of atelectasis and its contribution to acute lung injury will improve our approach to the prevention and management of atelectasis.
报告肺不张对围手术期结局的影响。肺不张发生于大多数接受麻醉患者肺部的低垂部位。肺不张的发生与肺顺应性降低、氧合受损、肺血管阻力增加以及肺损伤的发生相关。在此,我们探讨肺不张的病因、促成因素、后果、诊断及治疗。
肺不张描述的是因肺泡萎陷导致的肺泡内无气体状态,但最新研究结果表明肺泡内充满泡沫和液体。目前已知肺不张在异常气体交换之外发挥重要作用,并且在部分术后患者群体中预防或逆转肺不张可能改善结局。
在存在基础肺部疾病或心肺储备有限的情况下,肺不张可能产生重大后果。对肺不张的潜在本质及其对急性肺损伤的影响的进一步了解,将改善我们对肺不张的预防和管理方法。