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[Rebagliati医院进展期胃癌D1与D2淋巴结清扫术的对比研究]

[Comparative study of D1 and D2 ganglionic dissection in advanced gastric cancer at Rebagliati Hospital].

作者信息

Cornejo Consuelo, Portanova Michel

机构信息

Ex Médico Residente de Cirugía Hospital Rebagliati.

出版信息

Rev Gastroenterol Peru. 2006 Oct-Dec;26(4):351-6.

Abstract

Gastrectomy with D2 lymphadenectomy is the standard surgical procedure in most hospitals in Peru due to the fact that this Japanese surgical technique has proven to provide the best results in the world. However, no comparative study of the results of D1 and D2 lymphadenectomies has ever been performed in our country. This retrospective cohort study compares D2 lymphadenectomy versus D1 in surgical treatment of gastric cancer.Between January 2000 and December 2002, 316 patients underwent surgery at the Rebagliati National Hospital and a total of 100 patients were randomly selected, 50 of which underwent a D1 lymphadenectomy and 50 a D2 lymphadenectomy. Mortality rates were 8% for D1 lymphadenectomy and 4% for D2, whereas morbidityrates were 24% for D1 and 12% for D2. Survival after 3 years was 36% for D1 and 56% for D2 thus establishing a statistically significant difference (p = 0.04). We recommend gastrectomy with D2 lymphadenectomy as the surgical treatment of choice for advanced gastric cancer.

摘要

在秘鲁的大多数医院,胃切除术加D2淋巴结清扫术是标准的外科手术,因为这种日本外科技术已被证明在全球能提供最佳治疗效果。然而,我国从未进行过D1和D2淋巴结清扫术结果的比较研究。这项回顾性队列研究比较了D2淋巴结清扫术与D1淋巴结清扫术在胃癌外科治疗中的效果。2000年1月至2002年12月期间,316例患者在国家雷瓦利亚蒂医院接受了手术,共随机选取100例患者,其中50例行D1淋巴结清扫术,50例行D2淋巴结清扫术。D1淋巴结清扫术的死亡率为8%,D2淋巴结清扫术为4%;而发病率D1为24%,D2为12%。D1组3年后生存率为36%,D2组为56%,因此存在统计学显著差异(p = 0.04)。我们建议将胃切除术加D2淋巴结清扫术作为进展期胃癌的首选外科治疗方法。

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