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困难临床情况下的“全胃游离(TGD)”

"Total Gastric Dissociation (TGD)" in difficult clinical situations.

作者信息

Lall A, Morabito A, Bianchi A

机构信息

Department of Paediatric Surgery, Royal Manchester Children's Hospital, Manchester, UK.

出版信息

Eur J Pediatr Surg. 2006 Dec;16(6):396-8. doi: 10.1055/s-2006-924731.

Abstract

BACKGROUND

Since the first report by Bianchi in 1997, TOGD has been found to be safe and effective in patients with gastro-oesophageal reflux (GOR) with neurological impairment. This paper explores the versatility of total gastric dissociation (TGD) in difficult clinical situations.

METHODS

The medical records of 11 neurologically normal children treated with TGD and gastrostomy after failure of conventional procedures between 1999 and 2004 were reviewed with respect to demographic data, initial diagnosis, previous operations, postoperative complications, feeding pattern, and follow-up.

RESULTS

There were 7 males and 4 females. The mean age at operation was 52.7 months (24 to 72 m). The indications were severe colo-oesophageal reflux in 3; 1 post-fundoplication necrotic stomach; 1 gastric remnant after subtotal gastrectomy for bleeding; 1 microgastria; 2 with severe oesophageal obstruction following repeated failed repair of congenital stenosis of the oesophagus and after fundoplication; 1 congenital short oesophagus with left-sided congenital diaphragmatic hernia; and 2 with severe dysfunctional oesophagus following repair of congenital tracheo-oesophageal cleft. Full oral or gastrostomy feeding was established by the 5th postoperative day. The average follow-up was 47.2 months (24-72 months). There were 4 late deaths in the group: 2 with respiratory failure, 1 with sepsis secondary to peritonitis (small bowel herniation into the thorax) and 1 with pneumococcal infection. Seven patients are alive and thriving with markedly reduced episodes of chest infections and hospitalizations.

CONCLUSIONS

In this study TGD presented with no peri-operative morbidity and mortality and had good long-term results. The procedure offers a safe alternative for neurologically normal children after the failure of conventional surgical procedures.

摘要

背景

自1997年比安奇首次报告以来,已发现经胸胃底折叠术(TOGD)在患有神经功能障碍的胃食管反流(GOR)患者中是安全有效的。本文探讨了全胃游离术(TGD)在困难临床情况下的适用性。

方法

回顾了1999年至2004年间11例经传统手术失败后接受TGD和胃造口术治疗的神经功能正常儿童的病历,内容包括人口统计学数据、初始诊断、既往手术、术后并发症、喂养方式和随访情况。

结果

男性7例,女性4例。手术时的平均年龄为52.7个月(24至72个月)。手术指征包括:3例严重结肠食管反流;1例胃底折叠术后坏死胃;1例因出血行胃大部切除术后的胃残余;1例小胃畸形;2例先天性食管狭窄反复修复失败及胃底折叠术后严重食管梗阻;1例先天性短食管合并左侧先天性膈疝;2例先天性气管食管瘘修复术后严重食管功能障碍。术后第5天建立了完全经口或胃造口喂养。平均随访47.2个月(24至72个月)。该组有4例晚期死亡:2例呼吸衰竭,1例继发于腹膜炎(小肠疝入胸腔)的败血症,1例肺炎球菌感染。7例患者存活且状况良好,胸部感染和住院次数明显减少。

结论

在本研究中,TGD无围手术期发病率和死亡率,且长期效果良好。该手术为传统手术失败后的神经功能正常儿童提供了一种安全的替代方案。

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