Combs Barry G, Passey Megan, Michael Audrey, Pang Tikki, Lightfoot Dianne, Alpers Michael P
Papua New Guinea Institute of Medical Research, Goroka, World Health Organization, Geneva, Switzerland.
P N G Med J. 2005 Sep-Dec;48(3-4):158-67.
The prevalence of typhoid in the Papua New Guinea (PNG) highlands region increased rapidly in the mid-1980s, and now remains endemic. In this study ribotyping has been used to examine the number and types of Salmonella enterica serovar Typhi strains present during the 1977-1996 period. The ribotyping banding pattern results were based on Cla I and Eco RV digests. The 57 PNG isolates were divided into 11 different ribotypes. Comparison of ribotypes using coefficient of similarity values revealed a diverse group of ribotypes. Several strains appear to be endemic in PNG For instance, ribotypes 1, 2 and 3 were most commonly found among PNG isolates and isolates with these ribotypes have been cultured over a period of at least 11 years (1985-1996). Ribotype 3 was also observed in isolates from Malaysia and Thailand. Also found in PNG were ribotypes 4, 5, 6, 7, 8, 9, 16 and 17. The ribotyping suggests that serovar Typhi strains present in PNG include unique strains of serovar Typhi and also strains that are common to other countries.
20世纪80年代中期，巴布亚新几内亚（PNG）高地地区伤寒的流行率迅速上升，目前仍然流行。在本研究中，核糖体分型已被用于检测1977年至1996年期间存在的肠炎沙门氏菌伤寒血清型菌株的数量和类型。核糖体分型条带模式结果基于Cla I和Eco RV酶切。57株PNG分离株被分为11种不同的核糖体分型。使用相似系数值对核糖体分型进行比较，结果显示为一组多样的核糖体分型。几种菌株似乎在PNG地方流行。例如，核糖体分型1、2和3在PNG分离株中最常见，具有这些核糖体分型的分离株已培养了至少11年（1985年至1996年）。在马来西亚和泰国的分离株中也观察到核糖体分型3。在PNG还发现了核糖体分型4、5、6、7、8、9、16和17。核糖体分型表明，PNG存在的伤寒血清型菌株包括伤寒血清型的独特菌株以及其他国家常见的菌株。
