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本文引用的文献

1
Small-molecule agonists for the glucagon-like peptide 1 receptor.胰高血糖素样肽-1受体的小分子激动剂。
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):937-42. doi: 10.1073/pnas.0605701104. Epub 2007 Jan 9.
2
A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice.一种对糖尿病db/db小鼠有效的胰高血糖素样肽1受体非肽类激动剂。
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):943-8. doi: 10.1073/pnas.0610173104. Epub 2007 Jan 9.
3
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.肠促胰岛素系统：2型糖尿病中的胰高血糖素样肽-1受体激动剂和二肽基肽酶-4抑制剂
Lancet. 2006 Nov 11;368(9548):1696-705. doi: 10.1016/S0140-6736(06)69705-5.
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New sources of pancreatic beta-cells.胰腺β细胞的新来源。
Nat Biotechnol. 2005 Jul;23(7):857-61. doi: 10.1038/nbt1115.
5
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes.艾塞那肽（艾塞那肽-4）对二甲双胍治疗的2型糖尿病患者30周血糖控制及体重的影响。
Diabetes Care. 2005 May;28(5):1092-100. doi: 10.2337/diacare.28.5.1092.
6
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea.艾塞那肽（艾塞那肽-4）对接受二甲双胍和磺脲类药物治疗的2型糖尿病患者30周血糖控制的影响。
Diabetes Care. 2005 May;28(5):1083-91. doi: 10.2337/diacare.28.5.1083.
7
Glucagon-related peptide 1 (GLP-1): hormone and neurotransmitter.胰高血糖素样肽1（GLP-1）：激素与神经递质。
Regul Pept. 2005 Jun 15;128(2):97-107. doi: 10.1016/j.regpep.2004.08.026.
8
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes.艾塞那肽（艾塞那肽-4）对磺脲类药物治疗的2型糖尿病患者30周血糖控制的影响。
Diabetes Care. 2004 Nov;27(11):2628-35. doi: 10.2337/diacare.27.11.2628.
9
Identification of alkylidene hydrazides as glucagon receptor antagonists.亚烷基酰肼作为胰高血糖素受体拮抗剂的鉴定。
J Med Chem. 2001 Sep 13;44(19):3141-9. doi: 10.1021/jm000547o.
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Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist.首个选择性小分子降钙素基因相关肽（CGRP）拮抗剂BIBN4096BS的药理学特性
Br J Pharmacol. 2000 Feb;129(3):420-3. doi: 10.1038/sj.bjp.0703110.

Nonpeptidic glucagon-like peptide 1 receptor agonists: a magic bullet for diabetes?

作者信息

Murphy K G, Bloom S R

机构信息

Department of Metabolic Medicine, Hammersmith Hospital, Imperial College London, Sixth Floor Commonwealth Building, Du Cane Road, London W12 0NN, United Kingdom.

出版信息

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):689-90. doi: 10.1073/pnas.0610679104. Epub 2007 Jan 9.

DOI:10.1073/pnas.0610679104
PMID:17213306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1783373/
Abstract
摘要