Kafatos I, Manios Y, Moschandreas J, Kafatos A
Department of Nutrition & Dietetics, Harokopio University of Athens, Athens, Greece.
Eur J Clin Nutr. 2007 Jul;61(7):837-45. doi: 10.1038/sj.ejcn.1602584. Epub 2007 Jan 10.
To examine the long-term effects of the 'Cretan Health and Nutrition Education Program' on blood pressure.
A representative population of 176 pupils (85 from the intervention schools and 91 from the control schools).
Blood pressure, dietary, anthropometrical and physical activity data were obtained at baseline (academic year 1992-1993) and at follow-up examination (academic year 2001-2002).
The findings of the current study revealed that the increase over the 10-year period in systolic (SBP) and diastolic blood pressure (DBP) was higher in the control group (CG) than in the intervention group (IG) (P=0.003 and P<0.001 respectively). Regarding dietary indices, the IG were found to have a significantly higher intake of potassium (P=0.018) and magnesium (P=0.011) compared to the CG. Furthermore, the decrease in body mass index (BMI) z-score observed in the IG was found to differentiate significantly from the increase observed in the CG (P=0.042). On the contrary, the increase in leisure time, moderate to vigorous physical activities (MVPA) observed in the IG, was found to differentiate significantly from the decrease observed in the CG (P=0.032). Intervention's effect on SBP was mediated by changes in MVPA (beta=-0.20, P=0.030) and BMI (beta=0.19, P=0.048). Similarly, intervention's effect on DBP was mediated by changes in MVPA (beta=-0.18, P=0.048), BMI (beta=0.26, P=0.007) and magnesium intake (beta=-0.20, P=0.048).
The findings of the current study are encouraging, indicating favorable changes in blood pressure, micronutrients intake, BMI and physical activity over the 10 years of follow-up and 4 years after program's cessation, thus providing some support for the effectiveness of school-based health education programs in successfully tackling certain chronic disease risk factors early in life.
研究“克里特岛健康与营养教育项目”对血压的长期影响。
176名学生的代表性人群(85名来自干预学校,91名来自对照学校)。
在基线(1992 - 1993学年)和随访检查(2001 - 2002学年)时获取血压、饮食、人体测量和身体活动数据。
当前研究结果显示,对照组(CG)收缩压(SBP)和舒张压(DBP)在10年期间的升高幅度高于干预组(IG)(分别为P = 0.003和P < 0.001)。在饮食指标方面,发现IG组钾(P = 0.018)和镁(P = 0.011)的摄入量显著高于CG组。此外,发现IG组体重指数(BMI)z评分的下降与CG组观察到的升高有显著差异(P = 0.042)。相反,IG组休闲时间中度至剧烈身体活动(MVPA)的增加与CG组观察到的减少有显著差异(P = 0.032)。干预对SBP的影响通过MVPA(β = -0.20,P = 0.030)和BMI(β = 0.19,P = 0.048)的变化介导。同样,干预对DBP的影响通过MVPA(β = -0.18,P = 0.048)、BMI(β = 0.26,P = 0.007)和镁摄入量(β = -0.20,P = 0.048)的变化介导。
当前研究结果令人鼓舞,表明在10年随访期间以及项目停止4年后,血压、微量营养素摄入、BMI和身体活动出现了有利变化,从而为基于学校的健康教育项目在生命早期成功应对某些慢性病风险因素的有效性提供了一些支持。