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首次髋部骨折后的死亡率随时间变化趋势。

Time trends of mortality after first hip fractures.

作者信息

Giversen I M

机构信息

Danish Armed Forces Health Service, Koegevej 1, Gadstrup, DK-4000, Roskilde, Denmark.

出版信息

Osteoporos Int. 2007 Jun;18(6):721-32. doi: 10.1007/s00198-006-0300-1. Epub 2007 Jan 10.

DOI:10.1007/s00198-006-0300-1
PMID:17216129
Abstract

UNLABELLED

A register-based study including 2,674 first hip fracture patients from 1987-1996 investigated if the mortality after hip fracture was associated with time trend and fracture type. Despite significantly increasing age at admission no changing time trend of mortality was observed, nor was the mortality linked to the kind of fracture suffered.

INTRODUCTION AND HYPOTHESIS

A retrospective cohort study was performed to investigate if the mortality of first hip fracture patients was associated with time trend and fracture type. The hypotheses were that cumulative mortality would remain unchanged and there would be no difference in mortality between cervical and pertrochanteric patients.

METHODS

Study material was obtained by record linkage of excerpts from two computerized national health registers. First hip fractures were identified indirectly by searching the files ten years before the date of admission. The period 1987-1996 saw inclusion of 2,674 patients aged 50 years and older (average follow-up 2.6 years).

STATISTICS

Weighted regression analysis, chi(2) test, and t test.

RESULTS

Cumulative mortality did not change significantly (P > 0.05). Weighted average cumulative mortality was 9% (95% CI, 7.9-10.1) at 1 month, 15.5% (95% CI, 14.1-16.8) at 3 months, 26.5% (95% CI, 24.7-28.3) at 1 year, and 36.2% (95% CI, 34.1-38.3) at 2 years. Cervical and pertrochanteric first hip fracture patients did not have significantly different mortality rates (P > 0.05).

CONCLUSION

No changing time trend of mortality after first hip fracture was observed despite significantly increasing age at admission, nor was the mortality linked to the kind of fracture suffered.

摘要

未标注

一项基于登记的研究纳入了1987年至1996年间的2674例首次髋部骨折患者,旨在调查髋部骨折后的死亡率是否与时间趋势和骨折类型相关。尽管入院时年龄显著增加,但未观察到死亡率随时间的变化趋势,死亡率也与所遭受的骨折类型无关。

引言与假设

进行了一项回顾性队列研究,以调查首次髋部骨折患者的死亡率是否与时间趋势和骨折类型相关。假设是累积死亡率将保持不变,并且颈椎骨折和转子间骨折患者的死亡率没有差异。

方法

通过将两个计算机化的国家健康登记册中的摘录进行记录链接来获取研究材料。通过在入院日期前十年搜索文件间接识别首次髋部骨折。1987年至1996年期间纳入了2674例50岁及以上的患者(平均随访2.6年)。

统计学方法

加权回归分析、卡方检验和t检验。

结果

累积死亡率没有显著变化(P>0.05)。1个月时加权平均累积死亡率为9%(95%CI,7.9-10.1),3个月时为15.5%(95%CI,14.1-16.8),1年时为26.5%(95%CI,24.7-28.3),2年时为36.2%(95%CI,34.1-38.3)。颈椎骨折和转子间骨折的首次髋部骨折患者的死亡率没有显著差异(P>0.05)。

结论

尽管入院时年龄显著增加,但未观察到首次髋部骨折后死亡率随时间的变化趋势,死亡率也与所遭受的骨折类型无关。

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Survival after hip fracture.髋部骨折后的生存情况。
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