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通过环形减压融合术以最小的发病率成功治疗脊髓型颈椎病。

Successful treatment of cervical myelopathy with minimal morbidity by circumferential decompression and fusion.

作者信息

Aryan Henry E, Sanchez-Mejia Rene O, Ben-Haim Sharona, Ames Christopher P

机构信息

Department of Neurosurgery, UCSF Medical Center, University of California, 400 Parnassus Avenue, San Francisco, CA 94143-0350, USA.

出版信息

Eur Spine J. 2007 Sep;16(9):1401-9. doi: 10.1007/s00586-006-0291-9. Epub 2007 Jan 11.

Abstract

Circumferential cervical decompression and fusion (CCDF) is an important technique for treating patients with severe cervical myelopathy. While circumferential cervical decompression and fusion may provide improved spinal cord decompression and stability compared to unilateral techniques, it is commonly associated with increased morbidity and mortality. We performed a retrospective analysis of patients undergoing CCDF at the University of California, San Francisco (UCSF) between January 2003 and December 2004. We identified 53 patients and reviewed their medical records to determine the effectiveness of CCDF for improving myelopathy, pain, and neurological function. Degree of fusion, functional anatomic alignment, and stability were also assessed. Operative morbidity and mortality were measured. The most common causes of cervical myelopathy, instability, or deformity were degenerative disease (57%) and traumatic injury (34%). Approximately one-fifth of patients had a prior fusion performed elsewhere and presented with fusion failure or adjacent-level degeneration. Postoperatively, all patients had stable (22.6%) or improved (77.4%) Nurick grades. The average preoperative and postoperative Nurick grades were 2.1 +/- 1.9 and 0.4 +/- 0.9, respectively. Pain improved in 85% of patients. All patients had radiographic evidence of fusion at last follow-up. The most common complication was transient dysphagia. Our average clinical follow-up was 27.5 +/- 9.5 months. We present an extensive series of patients and demonstrate that cervical myelopathy can successfully be treated with CCDF with minimal operative morbidity. CCDF may provide more extensive decompression of the spinal cord and may be more structurally stable. Concerns regarding operation-associated morbidity should not strongly influence whether CCDF is performed.

摘要

颈椎后路减压融合术(CCDF)是治疗重度脊髓型颈椎病患者的一项重要技术。与单侧手术技术相比,颈椎后路减压融合术可能能更好地实现脊髓减压和稳定,但通常会增加发病率和死亡率。我们对2003年1月至2004年12月期间在加利福尼亚大学旧金山分校(UCSF)接受CCDF手术的患者进行了回顾性分析。我们确定了53例患者,并查阅了他们的病历,以确定CCDF在改善脊髓病、疼痛和神经功能方面的有效性。还评估了融合程度、功能解剖对线和稳定性。测量了手术发病率和死亡率。脊髓型颈椎病、不稳定或畸形的最常见原因是退行性疾病(57%)和创伤性损伤(34%)。约五分之一的患者曾在其他地方接受过融合手术,出现了融合失败或相邻节段退变。术后,所有患者的Nurick分级稳定(22.6%)或改善(77.4%)。术前和术后的平均Nurick分级分别为2.1±1.9和0.4±0.9。85%的患者疼痛得到改善。所有患者在最后一次随访时均有影像学融合证据。最常见的并发症是短暂性吞咽困难。我们的平均临床随访时间为27.5±9.5个月。我们展示了一系列广泛的患者病例,并证明CCDF能够成功治疗脊髓型颈椎病,且手术发病率最低。CCDF可能能更广泛地减压脊髓,并且在结构上可能更稳定。对手术相关发病率的担忧不应强烈影响是否进行CCDF手术。

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