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尼泊尔不丹难民的结核病治疗成功率很高。

High success rate of TB treatment among Bhutanese refugees in Nepal.

作者信息

Bam T S, Enarson D A, Hinderaker S G, Chapman R S

机构信息

College of Public Health, Chulalongkorn University, Bangkok, Thailand.

出版信息

Int J Tuberc Lung Dis. 2007 Jan;11(1):54-8.

Abstract

SETTING

Camps for refugees from Bhutan in south-east Nepal.

OBJECTIVES

To evaluate the outcome of treatment of tuberculosis (TB) cases in the refugee camps.

DESIGN

Cohort analysis of results of treatment of cases started on treatment from mid-July 1999 to mid-July 2004.

RESULT

A total of 1214 patients with TB were notified in the programme. Among these, 631 (52%) were new smear-positive pulmonary tuberculosis (PTB) cases, 175 (14%) new smear-negative PTB cases, 290 (24%) new extra-pulmonary TB (EPTB) cases and 118 (10%) smear-positive retreatment cases. Treatment success was achieved in 1061 (94%). The proportion of new non-smear-positive cases who died on treatment was significantly higher than the corresponding figure for new smear-positive cases (RR 7.57, 95%CI 3.74-15.32 for new smear-negative and 4.22, 95%CI 2.08-8.55 for EPTB).

CONCLUSION

High cure rates and low bacteriological failure rates can be achieved in refugee settings if there is close coordination and collaboration between the local health agencies and the National Tuberculosis Programme of the host country.

摘要

背景

尼泊尔东南部的不丹难民营地。

目的

评估难民营中结核病病例的治疗结果。

设计

对1999年7月中旬至2004年7月中旬开始治疗的病例的治疗结果进行队列分析。

结果

该项目共报告了1214例结核病患者。其中,631例(52%)为新涂阳肺结核病例,175例(14%)为新涂阴肺结核病例,290例(24%)为新肺外结核病例,118例(10%)为涂阳复治病例。1061例(94%)治疗成功。新非涂阳病例治疗期间死亡比例显著高于新涂阳病例(新涂阴病例相对危险度7.57,95%可信区间3.74 - 15.32;肺外结核病例相对危险度4.22,95%可信区间2.08 - 8.55)。

结论

如果当地卫生机构与东道国国家结核病项目之间密切协调与合作,在难民环境中可实现高治愈率和低细菌学失败率。

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