通过钯催化1-溴-5-甲基-1-芳基-己-1,5-二烯-3-醇衍生物的串联Heck环化反应合成（±）-β-紫穗槐烯酮的新方法。
Novel synthetic approach toward (+/-)-beta-cuparenone via palladium-catalyzed tandem Heck cyclization of 1-bromo-5-methyl-1-aryl-hexa-1,5-dien-3-ol derivatives.
作者信息
Ray Devalina, Ray Jayanta K
机构信息
Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, India.
出版信息
Org Lett. 2007 Jan 18;9(2):191-4. doi: 10.1021/ol062418t.
PMID:17217262
Abstract
A novel and convenient synthetic route toward (+/-)-beta-cuparenone and many other sesquiterpene natural product precursors has been developed via palladium-catalyzed tandem Heck cyclization of 1-bromo-5-methyl-1-aryl-hexa-1,5-dien-3-ols. [reaction: see text].
摘要
通过钯催化的1-溴-5-甲基-1-芳基-己-1,5-二烯-3-醇的串联Heck环化反应，已开发出一种新颖且便捷的合成（±）-β-紫穗槐二烯及许多其他倍半萜天然产物前体的路线。[反应：见正文]
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