在碱辅助下，利用单线态氧将官能化呋喃区域选择性和非对映选择性转化为丁烯内酯。
Base-assisted regio- and diastereoselective conversion of functionalized furans to butenolides using singlet oxygen.
作者信息
Patil Santoshkumar N, Liu Fei
机构信息
Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, NSW 2109, Australia.
出版信息
Org Lett. 2007 Jan 18;9(2):195-8. doi: 10.1021/ol062551l.
PMID:17217263
Abstract
A facile synthesis of beta-functionalized gamma-hydroxybutenolides was achieved using a Baylis-Hillman reaction followed by singlet oxygen oxidation. The conversion from 3-furfural was regio- and diastereoselective. [reaction: see text].
摘要
通过Baylis-Hillman反应，然后进行单线态氧氧化，实现了β-官能化γ-羟基丁烯内酯的简便合成。从3-糠醛的转化具有区域选择性和非对映选择性。[反应：见正文]
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