De Roover Arnaud, Detry Olivier, Desaive Claude, Maweja Sylvie, Coimbra Carla, Honoré Pierre, Meurisse Michel
Department of Abdominal Surgery and Transplantation, Centre Hospitalier Universitaire de Liège, University of Liège, Liège, Belgium.
Obes Surg. 2006 Dec;16(12):1656-61. doi: 10.1381/096089206779319419.
The authors discuss the potential influence of obesity surgery on the risk of cancer, focusing on the upper GI tract directly affected by operations. There is currently no substantiation for an increased risk of cancer after bariatric surgery, because there are only about 25 reports of subsequent cancer of the esophagus and the stomach. However, this review emphasizes the need to detect potential precancerous conditions before surgery. Candidates for postoperative endoscopic surveillance may include patients >15 years after gastric surgery, but also patients symptomatic for gastroesophageal reflux disease in whom a high incidence of Barrett's metaplasia has been reported. The greatest concern is a delay in diagnosis from inadequate investigation due to mistaking serious upper GI symptoms as a consequence of the past operation.
作者讨论了肥胖症手术对癌症风险的潜在影响，重点关注手术直接影响的上消化道。目前没有证据表明减肥手术后患癌风险增加，因为仅有约25例关于随后发生食管癌和胃癌的报告。然而，本综述强调在手术前检测潜在癌前病变的必要性。术后内镜监测的候选对象可能包括胃手术后15年以上的患者，以及有胃食管反流病症状且报告有巴雷特化生高发病率的患者。最令人担忧的是，由于将严重的上消化道症状误认为是过去手术的后果而导致调查不足，从而延误诊断。
