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[内镜下黏膜切除术/内镜黏膜下剥离术用于早期胃癌的切除]

[Endoscopic resection for early gastric cancers by EMR/ESD].

作者信息

Hoteya Shu, Yahagi Naohisa, Iizuka Toshiro, Kikuchi Daisuke, Kawano Kouichiro, Noguchi Tomoko, Mizuno Hideo, Hashimoto Mitsuyo

机构信息

Dept. of Gastroenterology, Toranomon Hospital.

出版信息

Gan To Kagaku Ryoho. 2007 Jan;34(1):16-20.

Abstract

The key issue in the field of therapeutic endoscopy in recent years is the development of a new therapeutic strategy for early gastric cancers using endoscopic submucosal dissection (ESD) technique. ESD was developed to overcome the problem of remnant or recurrent tumors after incomplete resection by conventional endscopic mucosal resection (EMR). Ever since after the emergence of ESD, indication criteria for endoscopic resection of early gastric cancers were extended through expansion of both theoretical and technical conditions. Complete en bloc resection rates were 96.7% and 62.6% in the ESD group and the EMR group, respectively, in our institution. ESD is a highly effective technique enabling us to resect much larger and difficult lesions, which cannot be resected by conventional EMR techniques. However, it involves a much higher complication rate and requires much higher skills. A small lesion less than 20 mm located in a good position can be resected completely, without any difficulties using conventional EMR techniques. Therefore, we must consider the approach to treatment, when conducting an endoscopic resection,it terms of the situation and skills of the endoscopist.

摘要

近年来,治疗性内镜领域的关键问题是利用内镜黏膜下剥离术(ESD)技术为早期胃癌开发一种新的治疗策略。ESD的开发是为了克服传统内镜黏膜切除术(EMR)不完全切除后残留或复发性肿瘤的问题。自从ESD出现后,通过理论和技术条件的扩展,早期胃癌内镜切除的适应证标准得以扩大。在我们机构,ESD组和EMR组的整块完整切除率分别为96.7%和62.6%。ESD是一种高效的技术,使我们能够切除传统EMR技术无法切除的更大、更困难的病变。然而,它的并发症发生率要高得多,并且需要更高的技术水平。位于良好位置的小于20mm的小病变,使用传统EMR技术可以毫无困难地完全切除。因此,在进行内镜切除时,我们必须根据内镜医师的情况和技术考虑治疗方法。

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