Van Goethem M, Schelfout K, Kersschot E, Colpaert C, Verslegers I, Biltjes I, Tjalma W A, De Schepper A, Weyler J, Parizel P M
Department of Radiology, University Hospital Antwerp, Antwerp, Belgium.
Eur J Radiol. 2007 May;62(2):273-82. doi: 10.1016/j.ejrad.2006.12.004. Epub 2007 Jan 12.
To determine the role of magnetic resonance (MR) mammography in detection and assessment of extent of tumors with extensive intraductal component (EIC+).
In a prospective study, 233 consecutive women with a suspicious lesion underwent preoperative MR mammography and 209 invasive ductal carcinomas were detected. We studied the prediction of intraductal spread on mammography (MX), ultrasound (US) and MR. We compared the size of the total lesion on MX, US and MR and correlated it with histopathology. Enhancement patterns on MR were described.
Of 209 invasive ductal carcinomas, 50 were EIC+ (24%). MX predicted intraductal spread in EIC+ carcinomas in 48.5%, US in 34.2% and MR in 68%. Compared to MX and US, MR was best in assessment of total tumor size. On MR, ductal spread in EIC+ tumors presented as ductal or linear enhancement, long spicules, a regional enhancing area or nodules adjacent to a mass.
MR had the highest sensitivity to predict intraductal spread and was superior in assessing total tumor size.
确定磁共振（MR）乳腺摄影在检测和评估具有广泛导管内成分（EIC+）的肿瘤范围中的作用。
在一项前瞻性研究中，233例连续的有可疑病变的女性接受了术前MR乳腺摄影，检测出209例浸润性导管癌。我们研究了乳腺X线摄影（MX）、超声（US）和MR对导管内扩散的预测情况。我们比较了MX、US和MR上总病变的大小，并将其与组织病理学进行关联。描述了MR上的强化模式。
在209例浸润性导管癌中，50例为EIC+（24%）。MX对EIC+癌导管内扩散的预测率为48.5%，US为34.2%，MR为68%。与MX和US相比，MR在评估肿瘤总体大小方面表现最佳。在MR上，EIC+肿瘤中的导管扩散表现为导管样或线性强化、长毛刺、局部强化区域或肿块旁的结节。
MR在预测导管内扩散方面具有最高的敏感性，在评估肿瘤总体大小方面更具优势。
