Van Goethem M, Schelfout K, Kersschot E, Colpaert C, Verslegers I, Biltjes I, Tjalma W A, Weyler J, De Schepper A
Department of Radiology, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium.
Eur Radiol. 2004 Aug;14(8):1363-70. doi: 10.1007/s00330-004-2295-3. Epub 2004 Mar 26.
The enhancing area surrounding breast carcinoma on MR mammography is correlated with findings from pathological examination. We studied 194 patients with breast cancer who underwent preoperative MR mammography. Of all malignant lesions presenting with an enhancing surrounding area on MR mammography, morphologic features including long spicules, a ductal pattern, diffuse enhancement or nodules were evaluated and compared with histopathological examination. A double breast coil was used; we performed a 3D FLASH sequence with contiguous coronal slices of 2 mm, before and after injection of 0.2 mmol/kg GD-DTPA, and subtraction images were obtained. In total, 297 malignant lesions were detected at MR mammography and 101 of them had one or more types of enhancing surrounding area. In 49 of the 53 cancers with long spicules and in 49 of the 55 cancers with surrounding ductal pattern of enhancement, pathological examination showed in situ and/or invasive carcinoma. Multiple nodules adjacent to the carcinoma were seen in 20 patients and corresponded with six cases of invasive and ten cases of ductal in situ carcinoma. A diffuse enhancing area next to a mass was seen in ten patients and consisted of carcinoma in all cases: seven in situ and three invasive carcinomas. Enhancing areas including long spicules, a ductal pattern, noduli, or diffuse enhancement surrounding a carcinoma corresponded with in situ or invasive extension of the carcinoma in 92.5, 89, 80 and 100% of cases, respectively.
乳腺磁共振成像（MR mammography）上乳腺癌周围的强化区域与病理检查结果相关。我们研究了194例术前行乳腺磁共振成像检查的乳腺癌患者。对于所有在乳腺磁共振成像上表现为周围强化区域的恶性病变，评估其形态学特征，包括长毛刺、导管样、弥漫性强化或结节，并与组织病理学检查结果进行比较。使用双侧乳腺线圈；在注射0.2 mmol/kg钆喷酸葡胺（GD-DTPA）前后，采用2 mm连续冠状位切片的三维快速低角度激发（3D FLASH）序列进行扫描，并获得减影图像。乳腺磁共振成像共检测到297个恶性病变，其中101个有1种或多种类型的周围强化区域。在53例有长毛刺的癌症中，49例以及在55例有周围导管样强化模式的癌症中，49例病理检查显示为原位癌和/或浸润癌。20例患者可见癌旁多个结节，对应6例浸润癌和10例导管原位癌。10例患者可见肿块旁弥漫性强化区域，所有病例均为癌：7例原位癌和3例浸润癌。癌周围包括长毛刺、导管样、小结节或弥漫性强化的强化区域分别在92.5%、89%、80%和100%的病例中与癌的原位或浸润性扩展相符。
