• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Effect of methyl methanesulphonate (MMS) and methylene dimethanesulphonate (MDMS) on the template activity of DNA isolated from MDMS-sensitive and -resistant Yoshida cells.

作者信息

Institoris E, Fox B W, Fox M

出版信息

Chem Biol Interact. 1975 Dec;11(6):501-6. doi: 10.1016/0009-2797(75)90026-5.

DOI:10.1016/0009-2797(75)90026-5
PMID:172243
Abstract

Both methylene dimethanesulphonate (MDMS) and methyl methanesulphonate (MMS) cause the template activity of Yoshida cell DNA to decrease in a dose-dependent manner. The MDMS-resistant subline of Yoshida tumour is less sensitive in terms of DNA template activity than the MDMS-sensitive subline towards both agents. Although the difference in sensitivity is not reflected in the survival data after each agent, it does suggest that the DNA from each cell line differs in its capacity to function as an efficient template.

摘要

相似文献

1
Effect of methyl methanesulphonate (MMS) and methylene dimethanesulphonate (MDMS) on the template activity of DNA isolated from MDMS-sensitive and -resistant Yoshida cells.
Chem Biol Interact. 1975 Dec;11(6):501-6. doi: 10.1016/0009-2797(75)90026-5.
2
DNA strand breaks and repair synthesis in Yoshida sarcoma: cells with differential sensitivities to bi-functional alkylating agents and UV light.
Mutat Res. 1981 Sep;83(2):233-49. doi: 10.1016/0027-5107(81)90008-7.
3
The effects of bifunctional alkylating agents on DNA synthesis in sensitive and resistant Yoshida cells.双功能烷化剂对敏感和耐药吉田细胞中DNA合成的影响。
Mutat Res. 1982 Aug;95(2-3):441-56. doi: 10.1016/0027-5107(82)90277-9.
4
The role of formaldehyde in methylene dimethanesulphonate-induced DNA cross-links and its relevance to cytotoxicity.
Chem Biol Interact. 1981 Dec;38(1):119-28. doi: 10.1016/0009-2797(81)90158-7.
5
A transferable "resistance factor" from in vitro cultured MDMS-resistant Yoshida sarcoma cells.来自体外培养的耐MDMS吉田肉瘤细胞的一种可转移“抗性因子” 。
Br J Cancer. 1973 Mar;27(3):245-52. doi: 10.1038/bjc.1973.29.
6
Comparative studies of DNA cross-linking reactions following methylene dimethanesulphonate and its hydrolytic product, formaldehyde.
Cancer Chemother Pharmacol. 1987;19(1):11-5. doi: 10.1007/BF00296247.
7
Collateral sensitivity between methylene dimethane sulfonate and halogenated methotrexate derivatives in the Yoshida sarcoma in vivo and in vitro.
J Natl Cancer Inst. 1977 Apr;58(4):955-8. doi: 10.1093/jnci/58.4.955.
8
The sensitivity of HeLa and Chinese hamster (ovary) cells to methylene dimethane sulphonate.HeLa细胞和中国仓鼠（卵巢）细胞对甲撑二甲磺酸盐的敏感性。
Chem Biol Interact. 1976 Jul;14(1-2):93-9. doi: 10.1016/0009-2797(76)90027-2.
9
Inhibition of rat liver RNA polymerases by action of the methylating agents dimethylnitrosamine in vivo and methyl methanesulfonate in vitro.体内二甲基亚硝胺和体外甲磺酸甲酯等甲基化剂作用对大鼠肝脏RNA聚合酶的抑制作用。
Cancer Res. 1976 May;36(5):1761-70.
10
Uptake studies of [14C] methylene dimethanesulphonate in bilaterally transplanted sensitive and resistant Yoshida sarcoma.[14C]亚甲基二磺酸甲酯在双侧移植的敏感和耐药吉田肉瘤中的摄取研究。
Chem Biol Interact. 1971 Jun;3(3):149-56. doi: 10.1016/0009-2797(71)90081-0.