Bashaw Greg J
Department of Neuroscience, University of Pennsylvania School of Medicine, 1113 BRB2/3, 421 Curie Boulevard, Philadelphia, PA 19104, USA.
Neuron. 2007 Jan 18;53(2):157-9. doi: 10.1016/j.neuron.2007.01.002.
The convergence of olfactory sensory axons that express the same receptor onto specific glomeruli is a common organizing principle in animal olfactory systems. In this issue of Neuron, two beautiful studies in Drosophila by Lattemann et al. and Sweeney et al. show that Semaphorin repulsion regulates interactions between olfactory receptor neurons to help axons find their correct targets.
表达相同受体的嗅觉感觉轴突汇聚到特定的嗅小球上，这是动物嗅觉系统中一种常见的组织原则。在本期《神经元》杂志中，拉特曼等人和斯威尼等人在果蝇身上进行的两项出色研究表明，信号素排斥作用调节嗅觉受体神经元之间的相互作用，以帮助轴突找到其正确的靶点。
