Lopez Manuel A, Shah Anil R, Westine John G, O'Grady Kevin, Toriumi Dean M
Department of Otolaryngology -- Head and Neck Surgery, Wilford Hall Medical Center, San Antonio, TX, USA.
Arch Facial Plast Surg. 2007 Jan-Feb;9(1):35-9. doi: 10.1001/archfaci.9.1.35.
To determine the impact of interventions on the degree of warping of costal cartilage.
The project was conducted at a large university animal research laboratory. The costal cartilage of eight 30-kg domestic pigs was harvested. The cartilage was cut into central and peripheral segments with a standard cutting die. Two sizes of rectangular cubes were compared. The central portions of costal cartilage were segmented and glued with octyl-2-cyanoacrylate. The shape of the cartilage was documented with both digital and film photography. The cartilage was placed into subdermal pockets on the dorsum of the pigs. The animals were killed at 4 weeks, and the cartilage was photographed. Adobe Photoshop software was used to measure the degree of warping. Statistical analysis was calculated by t test analysis.
A total of 115 rectangular costal cartilage blocks were treated. Large blocks warped less than small blocks (P<.02). Centrally cut blocks warped less than peripherally cut blocks (P<.03). The octyl-2-cyanoacrylate incited a significant sterile inflammatory response such that the blocks could not be accurately assessed for warpage.
Costal cartilage can be effectively used for grafting in rhinoplasty with minimal warping if large grafts from the central portion of cartilage are used.
确定干预措施对肋软骨弯曲程度的影响。
该项目在一所大型大学动物研究实验室进行。采集了8头30千克家猪的肋软骨。用标准切割模具将软骨切成中央段和外周段。比较了两种尺寸的长方体块。将肋软骨的中央部分进行分割并用2-氰基丙烯酸辛酯粘贴。用数码摄影和胶片摄影记录软骨的形状。将软骨放入猪背部的皮下袋中。4周后处死动物，并对软骨进行拍照。使用Adobe Photoshop软件测量弯曲程度。通过t检验分析进行统计分析。
共处理了115个长方形肋软骨块。大块的弯曲程度小于小块（P<0.02）。中央切割的块弯曲程度小于外周切割的块（P<0.03）。2-氰基丙烯酸辛酯引发了显著的无菌性炎症反应，以至于无法准确评估块的弯曲情况。
如果使用来自软骨中央部分的大移植物，肋软骨可有效地用于鼻整形术中的移植，且弯曲程度最小。
