Pirris Stephen M, Pollack Ian F, Snyderman Carl H, Carrau Ricardo L, Spiro Richard M, Tyler-Kabara Elizabeth, Kassam Amin B
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Childs Nerv Syst. 2007 Apr;23(4):377-84. doi: 10.1007/s00381-006-0281-6. Epub 2007 Jan 17.
Clival chordomas are rare tumors, especially in the pediatric population. In this report, we present the case of a 3-year-old boy who was found to have a large posterior pharyngeal, clival, and posterior fossa tumor detected on a CT scan after a closed head injury.
Further questioning revealed a history of ataxia and dysphagia. Imaging confirmed severe extrinsic brain stem compression. The tumor was resected in multiple stages utilizing a minimally invasive endoscopic endonasal technique along with open transfacetal, transcondylar approach through the carotid-vertebral window. The child suffered no permanent complications as a result of our treatment and his dysphagia significantly improved. Although a complete resection was not feasible due to vascular encasement by the tumor, extensive decompression was obtained with minimal morbidity.
We present this case to illustrate a new paradigm of skull base surgical approaches for large clival lesions in pediatric patients that allows aggressive resection with minimal morbidity.
斜坡脊索瘤是罕见肿瘤,在儿童群体中尤为少见。在本报告中,我们呈现了一名3岁男孩的病例,该男孩在闭合性颅脑损伤后进行CT扫描时,被发现患有巨大的咽后、斜坡及后颅窝肿瘤。
进一步询问发现有共济失调和吞咽困难病史。影像学检查证实存在严重的脑干外部压迫。采用微创内镜经鼻技术以及通过颈动脉 - 椎间隙的开放经小关节、经髁入路,分多个阶段切除肿瘤。我们的治疗未给患儿带来永久性并发症,其吞咽困难也有显著改善。尽管由于肿瘤包绕血管无法实现完整切除,但实现了广泛减压且并发症极少。
我们展示此病例以阐明小儿患者大型斜坡病变颅底手术入路的新模式,该模式能够以最低的并发症率进行积极切除。