Marec-Bérard Perrine, Crassard Nicolas, Schell Matthias, Philip Thierry, Thiesse Philippe, Ranchin Bruno, Frappaz Didier
Department of Pediatrics, Centre Léon Bérard, Lyon Cedex, France.
Pediatr Blood Cancer. 2008 Mar;50(3):690-2. doi: 10.1002/pbc.21117.
A 16-year old female presented painful masses in the lumbar region 5 years after the initial diagnosis of a localized osteosarcoma of the tibia. Abdominal X-ray revealed calcified masses. A bone scan confirmed an increased uptake in the renal areas. An ultrasound-guided fine needle biopsy confirmed the diagnosis of metastases. The procedure was complicated by subcapsular hemorrhage and gross hematuria. Renal metastases from osteosarcoma are usually asymptomatic and invisible on abdominal X-rays. The diagnosis is generally established by radionuclide bone scan or abdominal CT-scan. Our observation suggests that histological documentation of these unusual clinical presentations should be carefully weighed against the risk of the procedure.
一名16岁女性在最初诊断为胫骨局限性骨肉瘤5年后，腰部出现疼痛性肿块。腹部X线检查显示有钙化肿块。骨扫描证实肾脏区域摄取增加。超声引导下细针穿刺活检确诊为转移瘤。该操作并发了包膜下出血和肉眼血尿。骨肉瘤的肾转移通常无症状，腹部X线检查也无法显示。诊断一般通过放射性核素骨扫描或腹部CT扫描来确定。我们的观察表明，对于这些不寻常临床表现的组织学记录，应仔细权衡该操作的风险。
