Jia Xiupeng, Zhang Dongsheng, Zheng Jie, Gu Ning, Zhu Weichang, Fan Xiangshan, Jin Liqiang, Wan Meiling, Li Qunhui
School of Basic Medical Science, Southeast University, Nanjing 210009, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2006 Dec;23(6):1263-6.
With the sulfate as the materials and NaOH as precipitator, Mn(0.4)Zn(0.6)Fe2O4 nanoparticles were produced, which are proved to be spinel Mn-Zn ferrite analyzed by X-ray diffraction(XRD). Their shapes are approximately global examined by transmission electron microscopy(TEM) and their average diameter is 50 nm measured with image analysis-system. The Curie temperature was measured and in vitro heating test in a alternating magnetic field was carried out. The results show that the Curie temperature is 105. 407 degrees C, While its magnetic fluid could rise to 43 degrees C - 47 degrees C due to different concentration in a alternating magnetic field. The result provide theoretical and practical evidence to select an appropriate material and concentration for tumor
以硫酸盐为原料，氢氧化钠为沉淀剂，制备了Mn(0.4)Zn(0.6)Fe2O4纳米颗粒，经X射线衍射(XRD)分析证明其为尖晶石型锰锌铁氧体。通过透射电子显微镜(TEM)观察其形状近似球形，利用图像分析系统测得其平均直径为50nm。测量了居里温度，并在交变磁场中进行了体外加热试验。结果表明，居里温度为105.407℃，而其磁流体在交变磁场中因浓度不同可升温至43℃ - 47℃。该结果为选择合适的材料和浓度用于肿瘤治疗提供了理论和实践依据 。
