[多功能铁氧体磁性纳米粒子的表面修饰及其在生物医学中的研究进展]
[Surface modification of multifunctional ferrite magnetic nanoparticles and progress in biomedicine].
作者信息
Zhang Linxue, Alifu Nuernisha, Lan Zhongwen, Yu Zhong, Li Qifan, Jiang Xiaona, Wu Chuanjian, Sun Ke
机构信息
School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu 610054, P. R. China.
School of Medical Engineering and Technology, Xinjiang Medical University, Urumqi 830017, P. R. China.
出版信息
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2023 Apr 25;40(2):378-383. doi: 10.7507/1001-5515.202209056.
Magnetic ferrite nanoparticles (MFNPs) have great application potential in biomedical fields such as magnetic resonance imaging, targeted drugs, magnetothermal therapy and gene delivery. MFNPs can migrate under the action of a magnetic field and target specific cells or tissues. However, to apply MFNPs to organisms, further modifications on the surface of MFNPs are required. In this paper, the common modification methods of MFNPs are reviewed, their applications in medical fields such as bioimaging, medical detection, and biotherapy are summarized, and the future application directions of MFNPs are further prospected.
磁性铁氧体纳米颗粒（MFNPs）在磁共振成像、靶向给药、磁热疗法和基因递送等生物医学领域具有巨大的应用潜力。MFNPs 可在磁场作用下迁移并靶向特定细胞或组织。然而，要将 MFNPs 应用于生物体，需要对其表面进行进一步修饰。本文综述了 MFNPs 的常见修饰方法，总结了它们在生物成像、医学检测和生物治疗等医学领域的应用，并进一步展望了 MFNPs 的未来应用方向。
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