利用体细胞杂交克隆板将人类尿苷单磷酸激酶基因定位于1号染色体。
Assignment of the gene for human uridine monophosphate kinase to chromosome 1 using somatic cell hybrid clone panels.
作者信息
Satlin A, Kucherlapati R, Ruddle F H
出版信息
Cytogenet Cell Genet. 1975;15(3):146-52. doi: 10.1159/000130513.
PMID:172293
Abstract
Evidence from mouse-human somatic cell hybrids is presented for the assignment of the gene for uridine monophosphate kinase (ATP: nucleoside monophosphate phosphotransferase, E.C. 2.7.4.4) to human chromosome 1. The use of the "clone panel" in this determination and its value as a systematic method for gene mapping is discussed.
摘要
本文提供了来自小鼠-人类体细胞杂种的证据，证明尿苷单磷酸激酶（ATP：核苷单磷酸磷酸转移酶，E.C. 2.7.4.4）基因定位于人类1号染色体。讨论了在这一测定中使用“克隆板”及其作为基因定位系统方法的价值。
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