通过体细胞杂交将尿苷二磷酸半乳糖-4-表异构酶基因定位于人类第1号染色体，有证据表明该基因定位于1pter至1p21区域。
Assignment of a gene for uridine diphosphate galactose-4-epimerase to human chromosome 1 by somatic cell hybridization, with evidence for a regional assignment to 1pter yields 1p21.
作者信息
Benn P A, Shows T B, D'Ancona G G, Croce C M, Orkwiszewski K G, Mellman W J
出版信息
Cytogenet Cell Genet. 1979;24(3):138-42. doi: 10.1159/000131369.
PMID:477411
Abstract
The presence of human uridine diphosphate galactose-4-epimerase (GALE) was found to correlate with the presence of chromosome 1 in somatic cell hybrids between man and mouse. The gene for GALE can therefore be assigned to human chromosome 1. Using a chromosome 1 rearrangement, we have been able to regionally assign GALE to the pter yields p21 region.
摘要
已发现人类尿苷二磷酸半乳糖-4-表异构酶（GALE）的存在与人和小鼠体细胞杂种中1号染色体的存在相关。因此，GALE基因可定位于人类1号染色体。利用1号染色体重排，我们已能够将GALE基因定位到从染色体短臂末端到p21区域。
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