Rodríguez Duarte C
Policlínica Metropolitana, Caracas, Venezula.
Arch Esp Urol. 1991 Jul-Aug;44(6):697-700.
The results of prostatic specific antigen (PSA) determinations in 206 patients studied as a part of routine prostatic evaluation are presented. In 109 cases histologic evaluation was performed and a clinico-histologic correlation was made in all the 109 patients. We found 57 cases with benign prostatic hyperplasia (BPH), 36 cases with prostatic adenocarcinoma (PADC), 15 patients with prostatitis; and 1 patient with a leiomyoma of the prostate. When the PSA value is between 0-10 ng/ml no differential diagnosis between BPH and PADC can be made because there are no significant differences in these values. But with results above 15 ng/ml the diagnosis of PADC is more evident. Patients with permanent vesical catheter because of acute retention presented high values of PSA and it is possible to misinterpret the results and make an incorrect diagnosis of PADC. PSA is a very useful procedure in the pre and post-operative control of patients with radical prostatectomy. We consider it to be a useful tool in the diagnosis and treatment of cancer of the prostate and used together with the other diagnostic tests available.
本文展示了206例患者前列腺特异性抗原（PSA）检测结果，这些检测是作为常规前列腺评估的一部分进行的。其中109例进行了组织学评估，并对所有109例患者进行了临床-组织学相关性分析。我们发现57例良性前列腺增生（BPH）、36例前列腺腺癌（PADC）、15例前列腺炎患者；以及1例前列腺平滑肌瘤患者。当PSA值在0 - 10 ng/ml之间时，无法对BPH和PADC进行鉴别诊断，因为这些值没有显著差异。但当结果高于15 ng/ml时，PADC的诊断更为明显。因急性尿潴留而留置永久性膀胱导管的患者PSA值较高，可能会误判结果并对PADC做出错误诊断。PSA在前列腺癌根治术患者的术前和术后监测中是一项非常有用的检查。我们认为它是前列腺癌诊断和治疗的有用工具，可与其他可用的诊断测试一起使用。
