Dhingra Narendra, Gajdasty Adam, Neal Jim W, Mukherjee Achyut N, Lane Carol M
Cardiff Eye Unit, University Hospital of Wales, Cardiff CF14 4XW, UK.
Br J Ophthalmol. 2007 Jun;91(6):794-6. doi: 10.1136/bjo.2006.109892. Epub 2007 Jan 17.
To report a new technique of tissue preparation, using a marginal strip, after the excision of eyelid basal cell carcinomas (BCCs) and to report the long-term results of BCCs excised using this technique.
After the excision of eyelid BCC with a safety margin of 4 mm, a 1 mm strip was excised along the whole perimeter from the margin of the freshly excised specimen. This marginal strip had intact conjunctival mucosa along one edge and skin along the other. The marginal strip and the central tumour mass were then fixed immediately in formal saline and subjected to conventional histopathology.
Of the 61 patients who completed a 5 years follow-up, the results of 28 eye-lid BCCs that were within 4 mm of the lid margin are reported. The marginal strip was clear in 22 specimens and had the presence of residual tumour in its margin in 6 specimens. These six 6 cases were further managed by observation (n = 2), by further surgical excision using marginal strip (n = 2) and by Mohs' surgery (n = 2).
Marginal strip examines the entire resection margins analogous to Mohs' technique and we recommend its use in lid margin where tarsus is present throughout the specimen and >4 mm from the lid margin.
报告一种在眼睑基底细胞癌（BCC）切除术后使用边缘条带进行组织制备的新技术，并报告使用该技术切除BCC的长期结果。
在切除眼睑BCC并保留4mm安全切缘后，从新鲜切除标本的边缘沿整个周长切除一条1mm宽的条带。该边缘条带一边有完整的结膜黏膜，另一边有皮肤。然后将边缘条带和中央肿瘤块立即固定在福尔马林盐水中，并进行常规组织病理学检查。
在完成5年随访的61例患者中，报告了28例距睑缘4mm以内的眼睑BCC的结果。22个标本的边缘条带未见肿瘤，6个标本的边缘有残留肿瘤。这6例患者分别通过观察（n = 2）、再次使用边缘条带手术切除（n = 2）和莫氏手术（n = 2）进一步处理。
边缘条带类似于莫氏技术检查整个切除边缘，我们建议在整个标本中有睑板且距睑缘>4mm的睑缘处使用该技术。
