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[结直肠癌中与个体风险相关的后续护理?]

[Individual risk-related after-care in colorectal cancer?].

作者信息

Böhm B, Osswald J, Hucke H P, Stock W

机构信息

Chirurgische Abteilung, Marien-Hospitals, Düsseldorf, BRD.

出版信息

Langenbecks Arch Chir. 1991;376(6):314-22. doi: 10.1007/BF00186422.

Abstract

Efficacy of the regular follow-up program and influence on survival rate following treatment of recurrence were evaluated. 556 follow-up records of patients after resection of colorectal cancer were analysed. The primary drop-out rate was 12.4%. Recurrences were found in 26.6% (n = 128). 53.1% of recurrences were symptomatic at diagnosis of recurrence. Curative resection of recurrence was only performed in 19.5%. 46.1% were given palliative and 34.4 no specific oncologic treatment. We define efficacy as the rate of curative asymptomatic recurrence. This was 3.5% of all patients. From the curative resection of recurrence only 6 patients were free of recurrence longer than 2 years. No second resection of recurrence was possible. Different treatment of recurrence did influence the survival rate (p = 0.09). There was no difference in prognosis for asymptomatic and symptomatic recurrences (p greater than 0.8). In order to increase the efficacy of follow-up for colorectal cancer we are introducing a new concept based on individual risk factors.

摘要

评估了常规随访计划的疗效及其对复发治疗后生存率的影响。分析了556例结直肠癌切除术后患者的随访记录。主要失访率为12.4%。发现26.6%(n = 128)的患者出现复发。53.1%的复发在复发诊断时有症状。仅19.5%的复发行根治性切除。46.1%接受姑息治疗,34.4%未接受特定的肿瘤治疗。我们将疗效定义为根治性无症状复发率。这占所有患者的3.5%。在复发的根治性切除中,只有6例患者无复发超过2年。无法进行二次复发切除。不同的复发治疗确实影响生存率(p = 0.09)。无症状和有症状复发的预后无差异(p大于0.8)。为了提高结直肠癌随访的疗效,我们正在引入一种基于个体风险因素的新概念。

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