Yamakawa Noriyuki, Mochizuki Yoshirou, Nakahara Yasuharu, Kawamura Tetsuji, Sasaki Shin, Nishio Chihiro, Tsukamoto Hiroaki, Mizumori Yasuyuki, Mayumi Tetsuichirou, Kobashi Yoichiro
Department of Internal Medicine, Himeji Medical Center.
Nihon Kokyuki Gakkai Zasshi. 2006 Dec;44(12):933-7.
A 74-year-old man had been given a diagnosis of myelodysplastic syndrome (MDS), and had been treated with granulocyte-colony stimulating factor (G-CSF). 1 year later, he suffered from fever and his chest X-ray lung biopsy did not provide a diagnosis, video-assisted thoracoscopic lung biopsy was performed, which yielded a histological diagnosis of organizing pneumonia. His pulmonary disease was diagnosed as secondary organizing pneumonia due to MDS, and was treated successfully with steroids. Vigorous efforts to establish a histological diagnosis is needed for the antibiotics-resistant pneumonia in the case of MDS.
一名74岁男性被诊断为骨髓增生异常综合征(MDS),并接受了粒细胞集落刺激因子(G-CSF)治疗。1年后,他出现发热,胸部X线和肺活检均未明确诊断,遂进行了电视辅助胸腔镜肺活检,组织学诊断为机化性肺炎。他的肺部疾病被诊断为MDS继发的机化性肺炎,经类固醇治疗成功。对于MDS患者出现的抗生素耐药性肺炎,需要大力努力以确立组织学诊断。