Shears Stephen B
Inositide Signaling Group, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, PO Box 12233, NC 27709, USA.
Biochem Soc Symp. 2007(74):211-21. doi: 10.1042/BSS0740211.
Among the many derivatives of the inositol-based signalling family are a subgroup that possess diphosphates. In this review, some recent research into the actions of these specialized polyphosphates is analysed, and key goals for future studies are identified, which, it is hoped, will result in the wider cell-signalling community giving considerably greater attention to this intriguing but relatively neglected class of inositol polyphosphates.
在基于肌醇的信号传导家族的众多衍生物中,有一个亚组含有二磷酸酯。在这篇综述中,分析了最近对这些特殊多磷酸盐作用的一些研究,并确定了未来研究的关键目标,希望这将促使更广泛的细胞信号学界对这一有趣但相对被忽视的肌醇多磷酸盐类别给予更多关注。