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Vascular endothelium summary statement III: Cancer prevention and control.

作者信息

Reed Eddie, Seffrin John, Giavazzi Raffaella, van Hinsbergh Victor, Madeddu Paolo

机构信息

Division of Cancer Prevention and Control, NCCDPHP, CoCHP, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop K52, Atlanta, GA 30341 USA.

出版信息

Vascul Pharmacol. 2007 May;46(5):321-3. doi: 10.1016/j.vph.2006.10.018. Epub 2006 Nov 21.

DOI:10.1016/j.vph.2006.10.018
PMID:17234459
Abstract

The biology of vascular endothelium can be modulated through the use of pharmacologic agents. Whereas this has been explored to reasonable extent in cardiovascular disease, it is clear that the ability to modulate vascular endothelium for the purpose of cancer prevention is in its early stages. Among the unanswered questions, we do not understand under what circumstances such pharmacologic interventions might best be started; nor, how long such interventions might be used for a given individual. We present concepts for further exploration in the use of endothelial-active agents for cancer prevention and control; and, strategies for public health practice and research in this area.

摘要

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