Zhang Juntao, Koert Andrew, Gellman Barry, Gempp Thomas M, Dasse Kurt A, Gilbert Richard J, Griffith Bartley P, Wu Zhongjun J
Artificial Organs Laboratory, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
ASAIO J. 2007 Jan-Feb;53(1):23-31. doi: 10.1097/01.mat.0000247043.18115.f7.
A miniature Maglev blood pump based on magnetically levitated bearingless technology is being developed and optimized for pediatric patients. We performed impeller optimization by characterizing the hemodynamic and hemocompatibility performances using a combined computational and experimental approach. Both three-dimensional flow features and hemolytic characteristics were analyzed using computational fluid dynamics (CFD) modeling. Hydraulic pump performances and hemolysis levels of three different impeller designs were quantified and compared numerically. Two pump prototypes were constructed from the two impeller designs and experimentally tested. Comparison of CFD predictions with experimental results showed good agreement. The optimized impeller remarkably increased overall pump hydraulic output by more than 50% over the initial design. The CFD simulation demonstrated a clean and streamlined flow field in the main flow path. The numerical results by hemolysis model indicated no significant high shear stress regions. Through the use of CFD analysis and bench-top testing, the small pediatric pump was optimized to achieve a low level of blood damage and improved hydraulic performance and efficiency. The Maglev pediatric blood pump is innovative due to its small size, very low priming volume, excellent hemodynamic and hematologic performance, and elimination of seal-related and bearing-related failures due to adoption of magnetically levitated bearingless motor technology, making it ideal for pediatric applications.
一种基于磁悬浮无轴承技术的微型磁悬浮血泵正在为儿科患者进行研发和优化。我们采用计算与实验相结合的方法，通过表征血流动力学和血液相容性性能来进行叶轮优化。使用计算流体动力学（CFD）模型分析了三维流动特征和溶血特性。对三种不同叶轮设计的液压泵性能和溶血水平进行了数值量化和比较。根据这两种叶轮设计制造了两个泵原型并进行了实验测试。CFD预测结果与实验结果的比较显示出良好的一致性。与初始设计相比，优化后的叶轮使泵的整体液压输出显著提高了50%以上。CFD模拟表明主流路中的流场干净且流线型。溶血模型的数值结果表明没有明显的高剪切应力区域。通过CFD分析和台架测试，对小型儿科泵进行了优化，以实现低水平的血液损伤，并提高液压性能和效率。磁悬浮儿科血泵具有创新性，因其尺寸小、预充量极低、血流动力学和血液学性能优异，且采用磁悬浮无轴承电机技术消除了与密封和轴承相关的故障，使其成为儿科应用的理想选择。
