Yaşar Sirin, Mansur A Tülin, Göktay Fatih, Sungurlu Faik, Vardar Aker Fügen, Ozkara Selvinaz
Deaprtment of Dermatology, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey.
J Dermatol. 2007 Feb;34(2):124-30. doi: 10.1111/j.1346-8138.2006.00231.x.
Lipedematous scalp (LS) and lipedematous alopecia (LA) are rare conditions of unknown etiology characterized by a thick and boggy scalp due to increase in the subcutaneous fat layer. Besides the changes in the texture of skin, varying degrees of hair loss are seen in patients with LA. In this report, we present two cases with LA and one case with LS in white adults. On examination, a boggy and soft swelling of the scalp was detected in all patients. In addition, the patients with LA had alopecic areas over the boggy scalp. Histopathologic examinations of skin biopsy specimens and magnetic resonance imaging of the scalp showed increased thickness of subcutaneous fat tissue in all patients. The exact etiopathogenesis of LA and LS remain unknown. These conditions may be either reactive or compansatory responses versus yet undetected stimuli, or represent a genetic tendency. Both of the these entities have been initially reported mostly in adult black females, however, we believe that LA and LS may well occur in white subjects and may be more widespread and frequently observed than previously supposed.
脂性头皮（LS）和脂性脱发（LA）是病因不明的罕见病症，其特征是由于皮下脂肪层增加导致头皮增厚且松软。除了皮肤质地变化外，LA患者还会出现不同程度的脱发。在本报告中，我们介绍了2例白人成年LA患者和1例白人成年LS患者。检查发现，所有患者的头皮均有松软的肿胀。此外，LA患者在松软的头皮上有脱发区域。皮肤活检标本的组织病理学检查和头皮磁共振成像显示，所有患者的皮下脂肪组织厚度均增加。LA和LS的确切发病机制尚不清楚。这些病症可能是对尚未检测到的刺激的反应性或代偿性反应，或者代表一种遗传倾向。这两种病症最初大多报道于成年黑人女性，然而，我们认为LA和LS在白人中也很可能发生，而且可能比之前认为的更为普遍和常见。
