Menzinger Sébastien, Kaya Gürkan
Department of Dermatology, University Hospital of Geneva, Geneva, Switzerland.
Department of Clinical Pathology, University Hospital of Geneva, Geneva, Switzerland.
Dermatopathology (Basel). 2020 Feb 7;6(4):260-265. doi: 10.1159/000505354. eCollection 2019 Oct-Dec.
Localized myxedema is an uncommon complication of Graves' disease. It is characterized by the accumulation of glycosaminoglycans, particularly hyaluronate. Here we describe the case of a 51-year-old female patient suffering from Graves' disease, who has presented for years a thickening of the scalp, consistent with myxedema, and successfully treated with repeated injections of hyaluronidase.
局限性黏液性水肿是格雷夫斯病的一种罕见并发症。其特征是糖胺聚糖尤其是透明质酸盐的积聚。在此,我们描述一例51岁患格雷夫斯病的女性患者,她多年来头皮增厚,符合黏液性水肿表现,并通过反复注射透明质酸酶成功治愈。