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[根据健康人群正常范围对特纳综合征女孩进行甲状腺体积评估]

[Thyroid volume evaluation in girls with Turner syndrome according to normal range for healthy population].

作者信息

Kucharska Anna M, Brzewski Michał, Czarnocka Barbara, Januszek-Trzciakowska Aleksandra, Rymkiewicz-Kluczyńska Barbara

机构信息

Katedra i Klinika Pediatrii i Endokrynologii AM w Warszawie, Warszawa.

出版信息

Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw. 2006;12(4):292-5.

Abstract

INTRODUCTION

Turner syndrome is a common chromosomal aberration. Among other features of that syndrome susceptibility to autoimmune diseases is well known. Most often there is Hashimoto's thyroiditis. Because of short stature the evaluation of thyroid volume according to chronological age seems to be not efficient. THE AIM of the study was to find an adequate method of thyroid volume evaluation in girls with Turner syndrome using standards for healthy children.

MATERIAL AND METHODS

54 girls with Turner syndrome were examined, mean age was 11 years and 9 months. Physical and ultrasonographic examination of thyroid gland was performed. The hormonal state and presence of antithyroid autoantibodies were evaluated. The thyroid volume was evaluated according to normal range (by Delange) for chronological and height age of each girl.

RESULTS

According to chronological age the thyroid volume was in normal range, but according to height age in 3 patients the thyroid volume was over 97 percentile. They were the same girls in whom we detected goiter according to physical examination.

CONCLUSIONS

We suggest that proposed method gives the possibility of an accurate evaluation of thyroid volume in patients with Turner syndrome and in other patients with growth deficiency.

摘要

引言

特纳综合征是一种常见的染色体畸变。该综合征的其他特征中,对自身免疫性疾病的易感性是众所周知的。最常见的是桥本甲状腺炎。由于身材矮小,根据实际年龄评估甲状腺体积似乎并不有效。本研究的目的是使用健康儿童的标准找到一种评估特纳综合征女孩甲状腺体积的适当方法。

材料与方法

对54名特纳综合征女孩进行了检查,平均年龄为11岁9个月。对甲状腺进行了体格检查和超声检查。评估了激素状态和抗甲状腺自身抗体的存在情况。根据每个女孩的实际年龄和身高年龄的正常范围(由德兰热制定)评估甲状腺体积。

结果

根据实际年龄,甲状腺体积在正常范围内,但根据身高年龄,3名患者的甲状腺体积超过了第97百分位数。他们就是我们通过体格检查发现有甲状腺肿的相同女孩。

结论

我们建议,所提出的方法能够准确评估特纳综合征患者以及其他生长发育迟缓患者的甲状腺体积。

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