Akyol Ali, Bicerol Banu, Ertug Sema, Ertabaklar Hatice, Kiylioglu Nefati
Adnan Menderes University, Medical Faculty, Department of Neurology, 09100 Aydin, Turkey.
Seizure. 2007 Apr;16(3):233-7. doi: 10.1016/j.seizure.2006.12.008. Epub 2007 Jan 17.
Increased seropositivity for Toxoplasma gondii and Toxocara canis have been observed in epileptic patients. Our aim is to determine whether there is any relationship between these agents and epilepsy in our cryptogenic epilepsy group.
We studied specific IgG antibodies against T. gondii and T. canis in 100 cryptogenic epileptic patients and 50 healthy volunteers that had no history of epilepsy in their first degree relatives. We studied T. gondii and T. canis-specific IgG antibody serum levels and compared the values of these two groups.
We found similar T. gondii and T. canis serum IgG antibodies in patients with cryptogenic epilepsy and in the control group, even though the control group included more animal owners.
We did not show any relationships between epilepsy and positive T. gondii and T. canis serology in our epileptic patients.
癫痫患者中已观察到弓形虫和犬弓首蛔虫血清阳性率增加。我们的目的是确定在隐源性癫痫组中,这些病原体与癫痫之间是否存在任何关联。
我们研究了100例隐源性癫痫患者和50名一级亲属无癫痫病史的健康志愿者体内针对弓形虫和犬弓首蛔虫的特异性IgG抗体。我们研究了弓形虫和犬弓首蛔虫特异性IgG抗体血清水平,并比较了这两组的值。
我们发现,隐源性癫痫患者和对照组中弓形虫和犬弓首蛔虫的血清IgG抗体相似,尽管对照组中有更多的动物主人。
在我们的癫痫患者中,未发现癫痫与弓形虫和犬弓首蛔虫血清学阳性之间存在任何关联。