Anwaruddin Saif, Askari Arman T, Topol Eric J
Department of Cardiovascular Medicine, The Cleveland Clinic, Cleveland, Ohio, USA.
J Am Coll Cardiol. 2007 Jan 23;49(3):279-89. doi: 10.1016/j.jacc.2006.08.051. Epub 2007 Jan 4.
Acute coronary syndromes represent a complex phenotype involving the interplay of many elements. The risk of developing an acute coronary syndrome and related complications has been defined by variables such as age, diabetes, smoking history, serum creatine phosphokinase, or electrocardiographic findings. However, in the past 5 years the wide-scale acceptance of a protein--troponin--has changed the diagnostic profile. With advances in molecular medicine, this protein is a segue to a panel of molecular assays that will improve screening and tailored intervention. We expound upon some of these factors and the potential they may carry in changing clinical medicine.
