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急性脑损伤中的非神经器官功能障碍

Non-neurologic organ dysfunction in acute brain injury.

作者信息

Berthiaume Luc, Zygun David

机构信息

Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada.

出版信息

Crit Care Clin. 2006 Oct;22(4):753-66; abstract x. doi: 10.1016/j.ccc.2006.09.002.

DOI:10.1016/j.ccc.2006.09.002
PMID:17239753
Abstract

Patients with acute brain injury are a distinct group within the ICU who may develop non-neurologic organ dysfunction in the absence of systemic injury or infection. This dysfunction may arise directly as a result of the brain injury or indirectly with complications of brain-specific therapies. This article reviews the current literature with respect to the incidence of organ dysfunction or failure and its association with outcome in patients with acute brain injury. Organ system-specific etiologic considerations and management are discussed.

摘要

急性脑损伤患者是重症监护病房(ICU)中的一个特殊群体,他们在没有全身性损伤或感染的情况下可能会出现非神经系统器官功能障碍。这种功能障碍可能直接由脑损伤引起,也可能间接由脑部特异性治疗的并发症导致。本文回顾了关于急性脑损伤患者器官功能障碍或衰竭的发生率及其与预后的关系的当前文献。还讨论了特定器官系统的病因学考量和管理。

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The effect of increased positive end expiratory pressure on brain tissue oxygenation and intracranial pressure in acute brain injury patients.呼气末正压通气对急性脑损伤患者脑组织氧合和颅内压的影响。
Sci Rep. 2023 Oct 3;13(1):16657. doi: 10.1038/s41598-023-43703-9.
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Fast Maturation of Splenic Dendritic Cells Upon TBI Is Associated With FLT3/FLT3L Signaling.创伤性脑损伤后脾脏树突状细胞的快速成熟与 FLT3/FLT3L 信号有关。
Front Immunol. 2022 Feb 24;13:824459. doi: 10.3389/fimmu.2022.824459. eCollection 2022.
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Early detection of nonneurologic organ failure in patients with severe traumatic brain injury: Multiple organ dysfunction score or sequential organ failure assessment?
重型颅脑损伤患者非神经器官功能衰竭的早期检测:多器官功能障碍评分还是序贯器官衰竭评估?
Indian J Crit Care Med. 2016 Oct;20(10):575-580. doi: 10.4103/0972-5229.192042.
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Traumatic brain injury and aeromedical evacuation: when is the brain fit to fly?创伤性脑损伤与航空医疗后送:何时适合飞行?
J Surg Res. 2010 Dec;164(2):286-93. doi: 10.1016/j.jss.2009.07.040. Epub 2009 Aug 26.