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1
Immune response and the B blood group locus in chickens.鸡的免疫反应与B血型位点
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2
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Diverse effects of bursectomy on humoral immune responses in the chicken.法氏囊切除对鸡体液免疫反应的多种影响。
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B-complex genetic control of immune response to HSA, (T,G)-A--L, GT and other substances in chickens.鸡对人血清白蛋白、（T，G）-A--L、GT及其他物质免疫反应的复合维生素B遗传控制
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Association of H-2 types with genetic control of immune responsiveness to IgA allotypes in the mouse.小鼠中H-2类型与对IgA同种异型免疫反应性的遗传控制的关联。
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Recombination between genes coding for immune response and the serologically determined antigens in the chickenB system.鸡 B 系统中免疫反应基因与血清学决定抗原之间的重组。
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An Mhc class I allele associated to the expression of T-dependent immune response in the house sparrow.一种与家麻雀中T细胞依赖性免疫反应表达相关的Mhc I类等位基因。
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Chicken MHC class I and II gene effects on antibody response kinetics in adult chickens.鸡主要组织相容性复合体I类和II类基因对成年鸡抗体应答动力学的影响。
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4
Genetic resistance to fowl cholera is linked to the major histocompatibility complex.
Immunogenetics. 1987;25(5):284-9. doi: 10.1007/BF00404420.

本文引用的文献

1
Relationship of blood type to histocompatibility in chickens.鸡的血型与组织相容性的关系。
Science. 1961 Oct 6;134(3484):1008-9. doi: 10.1126/science.134.3484.1008.
2
Influence of B locus blood groups on adult mortality and egg production in the White Leghorn chicken.B 位点血型对白来航鸡成年死亡率和产蛋量的影响。
Genetics. 1973 Sep;75(1):181-9. doi: 10.1093/genetics/75.1.181.
3
The H-2 system: past and present.H-2系统：过去与现在
Transplant Proc. 1973 Mar;5(1):11-21.

鸡的免疫反应与B血型位点

Immune response and the B blood group locus in chickens.

作者信息

Pevzner I, Nordskog A W, Kaeberle M L

出版信息

Genetics. 1975 Aug;80(4):753-9. doi: 10.1093/genetics/80.4.753.

DOI:10.1093/genetics/80.4.753
PMID:172405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213373/
Abstract

Chickens of three blood group genotypes, B1B1, B1B2 and B1B19, were compared in their ability to produce antibodies. The B locus is the major histocompatibility locus in this species. Homozygous B1 pullets had significantly higher adult mortality than did the B1 heterozygotes. In two separate experiments the B1B1 females produced significantly fewer antibodies to Salmonella pullorum than did the B1 heterozygotes. Also the B1B1 pullets responded with lower antibody titers following immunization with ferritin, bovine serum albumin and parainfluenza-3 virus, although the differences were not significant. The results of this study suggest that an immune response gene is associated with the major histocompatibility locus in chickens, paralleling the H-2 locus and Ir genes in mice.

摘要

对三种血型基因型（B1B1、B1B2和B1B19）的鸡产生抗体的能力进行了比较。B基因座是该物种的主要组织相容性基因座。纯合的B1母鸡成年后的死亡率显著高于B1杂合子。在两项独立实验中，B1B1雌性鸡产生的针对鸡白痢沙门氏菌的抗体明显少于B1杂合子。此外，用铁蛋白、牛血清白蛋白和副流感3病毒免疫后，B1B1母鸡的抗体滴度较低，尽管差异不显著。本研究结果表明，免疫反应基因与鸡的主要组织相容性基因座相关，这与小鼠的H-2基因座和Ir基因相似。