Haslik W, Kamolz L-P, Nathschläger G, Andel H, Meissl G, Frey M
Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Austria.
Burns. 2007 May;33(3):364-8. doi: 10.1016/j.burns.2006.07.021. Epub 2007 Jan 22.
Restoring function after hand burns plays a major role in the restitution of a quality of life. Thereby the reconstructed pliability of the grafted areas is of utmost importance for good hand function. The collagen elastin matrix Matriderm was evaluated as a dermal substitute for the treatment of severe hand burns. In a series of 10 patients, mean age 43 years, TBSA 22.8%, an early debridement and immediate grafting with the matrix and unmeshed skin graft was carried out in a one-stage procedure. In the early postoperative follow up an overall take rate of 97% was observed. In contrast to conventional skin grafts, the color of the skin grafts over the matrix appeared pale in the first few days, but after 2 weeks no difference was observed. After three months, pliability of the grafted area was excellent, (mean VSS 3.2+/-1.2). Full range of motion was achieved in all hands, no blisters and no unstable or hypertrophic scars occurred. Matriderm has proved to be a dermal substitute suitable for the treatment of hand burns. We therefore consider Matriderm as a promising dermal substitute for the treatment of severe hand burns.
手部烧伤后功能的恢复对生活质量的恢复起着重要作用。因此,移植区域重建后的柔韧性对于良好的手部功能至关重要。胶原蛋白弹性蛋白基质Matriderm被评估为治疗严重手部烧伤的真皮替代物。在一组10例平均年龄43岁、烧伤总面积为22.8%的患者中,采用一期手术进行早期清创,并立即用该基质和非网状皮肤移植片进行移植。术后早期随访观察到总体成活率为97%。与传统皮肤移植片不同,基质上的皮肤移植片在最初几天颜色显得苍白,但2周后未观察到差异。三个月后,移植区域的柔韧性极佳(平均温哥华瘢痕量表评分为3.2±1.2)。所有手部均实现了全关节活动范围,未出现水泡,也未出现不稳定或增生性瘢痕。Matriderm已被证明是一种适合治疗手部烧伤的真皮替代物。因此,我们认为Matriderm是治疗严重手部烧伤的一种有前景的真皮替代物。