Siewert J R, Fink U
Chirurgische Klinik und Poliklinik, Technischen Universität München.
Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990:275-83.
Oncologic surgery still is the fundamental principle of cancer therapy. This is only useful when leading to a complete tumor extirpation (so-called R0-resection). Under these conditions an improvement of prognosis can be achieved. Unfortunately this aim can only be reached in some 50-70% of our patients. For all the other patients non-surgical therapy in surgery has to be secured by oncologic surgery. A most interesting development takes at present the preoperative chemotherapy or radiation therapy respectively. The aim is down-staging of the tumor to make a final R0-resection possible after all.
肿瘤外科手术仍然是癌症治疗的基本原则。只有在实现肿瘤完全切除（即所谓的R0切除）时，这一原则才有用。在这种情况下，可以改善预后。不幸的是，只有约50%至70%的患者能够实现这一目标。对于所有其他患者，肿瘤外科手术必须确保手术中的非手术治疗。目前最有趣的进展是术前化疗或放疗。其目的是降低肿瘤分期，以便最终能够实现R0切除。
