Brière Jean-Jacques, Tzagoloff Alexander
Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
Mol Cell. 2007 Jan 26;25(2):176-8. doi: 10.1016/j.molcel.2007.01.007.
In the January 3 issue of Cell Metabolism, report that the mitochondrial metallochaperones Sco1 and Sco2, essential for cytochrome c oxidase assembly, are also responsible for maintenance of cell copper homeostasis, thus showing a new function of mitochondria.
在1月3日的《细胞代谢》杂志上,有报道称,细胞色素c氧化酶组装所必需的线粒体金属伴侣蛋白Sco1和Sco2,也负责维持细胞铜稳态,从而揭示了线粒体的一项新功能。