γ射线诱导斑马鱼成熟生殖细胞特定座位和隐性致死突变的频率。
Frequency of gamma-Ray Induced Specific Locus and Recessive Lethal Mutations in Mature Germ Cells of the Zebrafish, BRACHYDANIO RERIO.
机构信息
Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.
出版信息
Genetics. 1983 Jan;103(1):109-23. doi: 10.1093/genetics/103.1.109.
Abstract
Specific locus and recessive lethal mutations are induced by gamma-rays with approximately first order kinetics in the zebrafish (Brachydanio rerio) with frequencies of 4 x 10(-5) r(-1 ) and 4 x 10(-3) r(-1), respectively. The surprisingly low ratio (100:1) of recessive lethals to specific locus mutations may be due to the induction of large deficiencies by gamma-rays.
摘要
γ射线诱发斑马鱼（Brachydanio rerio）特定基因座和隐性致死突变的频率分别约为 4×10-5 r-1和 4×10-3 r-1，符合一级动力学。隐性致死突变与特定基因座突变的比值（100：1）出人意料地低，这可能是由于γ射线诱导了大的缺失。
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