Rangel H, Montero P, Espinosa F, Castillo F J
Departamento de alergia e inmunología, Hospital de Especialidades Centro Médico La Raza, Instituto Mexicano del Seguro Social.
Rev Alerg. 1991 Jul-Aug;38(4):105-9.
We performed a prospective study in patients with a medical history of adverse reaction to drugs with the purpose of rule out allergy. We included 31 patients who were attended in the Allergy Service. We compared the sensibility and specificity of the test of inhibition factor of leucocytes migration and degranulation basophil against the exposition. After the statistical analysis, we concluded: the laboratory test, we have already mentioned, have little sensibility and specificity so the exposition test in the quickest, useful, and more simple method to determine drugs allergy, but more dangerous.
我们对有药物不良反应病史的患者进行了一项前瞻性研究，目的是排除过敏。我们纳入了31名在过敏科就诊的患者。我们比较了白细胞迁移抑制因子试验和嗜碱性粒细胞脱颗粒试验对暴露的敏感性和特异性。经过统计分析，我们得出结论：我们已经提到的实验室检测敏感性和特异性较低，因此暴露试验是确定药物过敏最快、最有用且最简单的方法，但更危险。
