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大肠杆菌素生成因子 B 与 F 类因子之间的相互作用:分离对大肠杆菌素生成因子 B 作用不敏感的 F- lac 因子突变体。

Interactions between Colicinogenic Factor B and F-Type Factors: Isolation of a Mutant F-lac Factor Insensitive to the Effect of Colicinogenic Factor B.

机构信息

Departamento de Biología Celular, Facultad de Ciencias, U.C.V., Caracas, Venezuela.

出版信息

Genetics. 1972 Feb;70(2):205-13. doi: 10.1093/genetics/70.2.205.

Abstract

An extrachromosomal factor, colicinogenic factor B (colB) inhibits expression of fertility functions of various F-type factors in strains of E. coli K12. Mutant F-lac factors simultaneously became insensitive to all the effects of colB as well as to similar actions exerted by a resistance transfer factor, R fi(+). This suggests that a common site or activity necessary for the expression of several F functions is affected by products of both colB and R fi(+).

摘要

一种染色体外因子,大肠杆菌素生成因子 B(colB)抑制了大肠杆菌 K12 菌株中各种 F 型因子的育性功能的表达。突变 F- lac 因子同时对 colB 以及抗性转移因子 R fi(+)的所有作用变得不敏感。这表明,表达几种 F 功能所需的共同位点或活性受到 colB 和 R fi(+)产物的影响。

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引用本文的文献

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本文引用的文献

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Infective heredity of multiple drug resistance in bacteria.
Bacteriol Rev. 1963 Mar;27(1):87-115. doi: 10.1128/br.27.1.87-115.1963.
2
Characteristics of E. coli K12 strains carrying both an F prime and an R factor.
Genet Res. 1970 Aug;16(1):113-22. doi: 10.1017/s0016672300002329.
3
Repressor-insensitive mutants of the F sex factor.
J Mol Biol. 1970 Feb 28;48(1):177-9. doi: 10.1016/0022-2836(70)90227-5.

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