Department of Genetics and Cell Biology, University of Minnesota, St. Paul, Minnesota 55108.
Genetics. 1977 Oct;87(2):327-41. doi: 10.1093/genetics/87.2.327.
Ninety-five generations of stabilizing selection for pupa weight in Tribolium castaneum resulted in a significant decrease in phenotypic variance, moderate reductions in additive genetic variance, but only slight changes in heritability for the trait. Sterility was significantly lower and the average number of live progeny per fertile mating was significantly higher in populations where stabilizing selection was practiced as compared with random selected populations. The results indicate that more genetic variability is being maintained than would be expected unless a fraction of the genes have a heterozygote advantage on the fitness scale. The reduction in phenotypic variance indicated that the populations with stablizing selection became somewhat more buffered against environmental sources of variation over the course of the experiment.
经过 95 代对赤拟谷盗蛹重的稳定选择,表型方差显著降低,加性遗传方差适度减少,但该性状的遗传力仅有轻微变化。与随机选择种群相比,实施稳定选择的种群的不育率显著降低,每个可育交配的活后代数量显著增加。结果表明,与预期的情况相比,更多的遗传变异正在被维持,除非一部分基因在适应度尺度上具有杂合优势。表型方差的减少表明,在实验过程中,经过稳定选择的种群对环境变异源的缓冲能力有所增强。