Department of Zoology, The University of Iowa, Iowa City, Iowa 52242.
Genetics. 1978 Feb;88(2):391-403. doi: 10.1093/genetics/88.2.391.
Proof is offered that s approximately ig for all forms of selection where fitness is a nondecreasing function of a normally distributed phenotype (called fitness potential); s is selection coefficient, i is standard selection differential, and g is standard differential effect of a locus genotype.Evidence is presented that the cost of selection does not limit genic polymorphism; that truncation selection is not necessary for high cost-efficiency; and that opposing directions of selection in a heterogeneous environment do not reduce cost-efficiency critically.
证明表明,当适应度是正态分布表型(称为适应度潜力)的增函数时,s 大约为 ig,适用于所有形式的选择;s 是选择系数,i 是标准选择差,g 是基因座基因型的标准差异效应。本文提出,选择的代价不会限制基因多态性;高成本效率不需要截断选择;异质环境中选择的相反方向不会显著降低成本效率。